Assistant Professor
303D Bowne Hall
erjain@syr.edu
315.443.4050
Experience:
- Research Scientist, Washington University in Saint Louis
- Postdoctoral Fellow and Instructor, Saint Louis University
- Postdoctoral Associate, Virginia Tech
Degrees:
- Ph.D., Indian Institute of Technology Kanpur, India, 2011
- Bachelor’s in Pharmacy, India, 2004
Lab/Center Affiliation:
- Syracuse BioInspired Institute
Areas of Expertise:
- Targeted and programed drug delivery for macrophages
- Injectable and biodegradable hydrogels and scaffolds
- Musculoskeletal tissue engineering
- Drug Delivery
Inflammation is a primary component of all diseases including several musculoskeletal disorders such as arthritis. The Jain Lab research focuses on engineering immunomodulatory biomaterials for advancing treatment of musculoskeletal disorders and related inflammatory disorders. We are particularly interested in design of macrophage targeting and programed drug delivery systems for spatially and temporally controlled biomolecule release to regulate inflammation. We employ a combination of in vitro models and pre-clinical animal models to evaluate the translational potential of these novel delivery systems.
Honors and Awards
- 2021 Discovery Award (DoD)
- 2018 Travel Award for Best Poster, Musculoskeletal Research Center, Winter Symposium, Washington University in Saint Louis
- 2017 Best Undergraduate Poster Award to a mentee at STLAURUS 2017
- 2004-2010 Graduate Research Scholarship, Department of Biotechnology (DBT), India
- 2008 Travel grant for attending from Council of Scientific and Industrial Research (CSIR), India.
Selected Publications:
- I.M. Berke, E. Jain, B.Yavuz, T. McGrath, L. Jing, M. Silva, G. Mbalaviele, F. Guilak, D. Kaplan, L.A. Setton. NF-κB-mediated effects on behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis, Osteoarthritis and Cartilage (2021), 29, 248-256.
- E. Jain, S. Neal, H.Graf, X. Tan, R. Balasubramaniam, and N.Huebsch Copper-Free Azide–Alkyne Cycloaddition for Peptide Modification of Alginate Hydrogels ACS Applied Bio Materials (2021) 4 (2), 1229-1237.
- X, Tan, E. Jain, M.N. Barcellona, E. Morris, S. Neal, M.C. Gupta, J.M. Buchowski, M. Kelly, L.A. Setton, N. Huebsch: Integrin and syndecan peptide-conjugated alginate hydrogel for modulation of nucleus pulposus cell phenotype. Biomaterials. 2021.
- E. Jain, N.Chinzei, A. Blanco, N. Case, L. J. Sandell, S. Sell, M. F.Rai, S. P. Zustiak, Sustained release of platelet-rich plasma from polyethylene glycol hydrogels exerts beneficial effects on chondrocytes, J. Orthop. res. (https://doi.org/10.1002/jor.24404)
- E. Jain, A.S. Qayyum, G. Kolar, Y. Kim, S.A. Sell, S.P. Zustiak, Design of electrohydrodynamic sprayed polyethylene glycol hydrogel microspheres for cell encapsulation, Biofabrication 9 (2017) 025019.
- E. Jain, S. Sheth, A. Dunn, S.P. Zustiak, S.A. Sell, Sustained release of multicomponent platelet-rich plasma proteins from hydrolytically degradable PEG hydrogels, J Biomed Mater Res A 105 (2017) 3304-3314.
- E. Jain, L. Hill, E. Canning, S.A. Sell, S.P. Zustiak, Control of gelation, degradation and physical properties of polyethylene glycol hydrogels through the chemical and physical identity of the crosslinker, J Mater Chem B 5 (2017) 2679-2691.
- S.G. Priya, A. Gupta, E. Jain, J. Sarkar, A. Damania, P.R. Jagdale, B.P. Chaudhari, K.C. Gupta, A. Kumar, Bilayer Cryogel Wound Dressing and Skin Regeneration Grafts for the Treatment of Acute Skin Wounds, ACS Appl Mater Inter 8 (2016) 15145-15159.