Biomaterials/Tissue Engineering

Biomaterials science is the physical and biological study of materials and their interaction with the biological environment. Tissue engineering uses of a combination of cells, biomaterials, and biochemical and biomechanical factors, individually or in combination, to repair or replace tissues or organs. The Biomedical and Chemical Engineering Department at Syracuse University has a strong and growing emphasis on biomaterials and tissue engineering, and many faculty in the department are members of the recently created Syracuse Biomaterials Institute.

Research in the department includes disciplinary projects in biomaterials and in tissue engineering, as well as interdisciplinary projects at the interface of these two exciting research areas. These projects are nearly universally motivated by the potential to improve human health and well-being. Examples of current biomaterials and tissue engineering projects in the department are listed below:

  • Active Cell Culture
  • Biomineralization
  • Control of bacterial biofilm formation
  • Fragmentation Mechanisms of Bacterial Biofilms of Physiological Relevance
  • Freeform Fabrication of Biomaterials
  • Cartilage Tissue Engineering
  • Micromechanics of Wear of Ultrahigh Molecular Weight Polyethylene (UHMWPE)
  • Redox electrochemistry and metallic biocompatibility
  • The reduction half-cell and protein adsorption and interaction
  • Control of cell viability with redox electrochemistry
  • Smart medical devices with electrochemical monitoring
  • Fretting Corrosion of Medical Alloys and Devices
  • Electrochemical Atomic Force Microscopy of Metallic Biomaterials
  • Passive oxide films and their behavior in the biological milieu
  • Performance testing of orthopedic, spinal, and cardiovascular devices
  • Micro- and nano-indentation of polymeric biomaterials and tissue engineered constructs
  • Development of novel two solution bone cements for vertebroplasty, kyphoplasty and joint replacement
  • Modeling polymerization processes, residual stresses and porosity development in bone cements
  • Atomic Force microscopy for biomaterials, proteins, and cells
  • Nanoindentation testing of biomaterials
  • Viscoelastic analysis of nanomechanics
  • Nanoparticle development
  • Failure analysis of retrieved total joint replacements
  • In-vitro testing of corrosion mechanisms in medical devices
  • Fatigue and fracture testing of medical devices